laparoscopic ovarian drilling inclomiphene resistant pco patients: a preferred method of treatment

objective: to determine the efficacy of ovarian drilling in pco patients who failed to achieve pregnancy with medical treatment. methods and main results: 75 patients with a diagnosis of pco of whom 48(64%) were primary infertile and 27(36%) were secondary infertile were clomiphene resistant. the other methods like bromocriptin, gonadotropins, gnrh -a and metformin had been given to these patients for infertility treatment without benefit. after ovarian drilling, pregnancy was achieved in 41 patients (54.6%), 30(40%) in group i (primary infertile group) and 11 (14.6%) in group ii (secondary infertile group). during the operation adhesiolysis was necessary in 14( 18.6%) and removal of endometriotic lesions was indicated in 5(6.6%) in both groups. conclusion: ovarian drilling is an ideal technique in pco patients with failure of medical treatment, considering the benefit of also performing other necessary surgical interventions.